ALEXA FLUOR 350 Rabbit anti- BCA2 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated [IgG]

BCA2; Breast cancer associated gene 2; CL469780; Rabring 7; RING finger protein 115; RNF115; Zinc finger protein 364; RN115_HUMAN.

The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.