ALEXA FLUOR 350 Rabbit anti- Arfaptin 2 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated [IgG]
Výrobca: Bioss Katalógové č .: bs-1442R-A350 Aplikácie: Imunofluorescencia Reaktivita: Ostatné Pôvod: Rabbit Klonalita: Polyclonal Konjugáty: AlexaFluor 350 Laser: 355 nm (ultrafialový) Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:ARFIP2; arfaptin 2; ADP-ribosylation factor interacting protein 2; Partner of RAC1; POR1; ARFP2_HUMAN .
ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.
100ul
519,20 EUR
s DPH