Unconjugated Mouse anti-Human, Mouse, Rat IF4E (4C5) Monoclonal Antibody [IgG1]

CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; Eukaryotic translation initiation factor 4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.