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Unconjugated Rabbit anti-Human, Mouse, Rat, Monkey Post-synaptic density protein 95 Antibody [IgG]
Výrobca: Bioss Katalógové č .: bs-0179R Aplikácie: Imunofluorescencia, Imunohistochémia, Prietoková cytometria, ELISA, ELISPOT Reaktivita: Human, Mouse, Rat, Monkey Pôvod: Rabbit Klonalita: Polyclonal Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:PSD95; SAP9; SAP-9; Disks large homolog 4; Postsynaptic density protein 95; PSD-95; Synapse-associated protein 9; DLG4
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).