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Cy3 Rabbit anti-Human, Rat IL-1R2 Polyclonal Antibody, Cy3 Conjugated [IgG]
Výrobca: Bioss Katalógové č .: bs-2595R-Cy3 Aplikácie: Imunofluorescencia, Prietoková cytometria Reaktivita: Human, Rat Pôvod: Rabbit Klonalita: Polyclonal Konjugáty: Cy3 Laser: 561 nm (žltý) Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:IL1RB; CD121b; IL1R2c; CDw121b; IL-1R-2; IL-1RT2; IL-1RT-2; Interleukin-1 receptor type 2; CD121 antigen-like family member B; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; IL1R2
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.