Unconjugated Rabbit anti-Human, Mouse, Rat Histone H2A Polyclonal Antibody [IgG]

H2A; H2A/q; H2AFQ; H2A-GL101; Histone H2A type 2-C; Histone H2A-GL101; Histone H2A/q; HIST2H2AC

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.