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ALEXA FLUOR 350 Rabbit anti- HERC4 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated [IgG]
Výrobca: Bioss Katalógové č .: bs-15462R-A350 Aplikácie: Imunofluorescencia Reaktivita: Ostatné Pôvod: Rabbit Klonalita: Polyclonal Konjugáty: AlexaFluor 350 Laser: 355 nm (ultrafialový) Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:DKFZP564G092; HECT and RLD domain containing E3 ubiquitin protein ligase 4; HECT domain and RCC1 like domain containing protein 4; HECT domain and RCC1-like domain-containing protein 4; Hect domain and RLD 4; HERC 4; HERC4; HERC4_HUMAN; KIAA1593; Probable E3 ubiquitin protein ligase HERC4; Probable E3 ubiquitin-protein ligase HERC4.
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).