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Unconjugated Rabbit anti-Human, Mouse eNOS (Ser1177) Polyclonal Antibody [IgG]
Výrobca: Bioss Katalógové č .: bs-3447R Aplikácie: Western Blot, Imunofluorescencia, Imunohistochémia, Prietoková cytometria, ELISA, ELISPOT Reaktivita: Human, Mouse Pôvod: Rabbit Klonalita: Polyclonal Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:eNOS; ECNOS; Nitric oxide synthase, endothelial; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; NOS type III; NOSIII; NOS3
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.