Unconjugated Rabbit anti- DAPL1 Polyclonal Antibody [IgG]

dapL1; DAPL1_HUMAN; death associated protein-like 1; Death-associated protein-like 1; Early epithelial dferentiation-associated protein; EEDA; RP23-151F21.4.

In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved cytoplasmic region called the death domain_. DAPL1 (Death-associated protein-like 1), also known as EEDA (Early epithelial differentiation-associated protein), is a 107 amino acid protein that is expressed in hair follicles and is thought to function in a similar manner to DAP-1, possibly participating in the early stages of epithelial differentiation and/or apoptosis.