Unconjugated Rabbit anti-Human, Rat CD40L Polyclonal Antibody [IgG]

IGM; IMD3; TRAP; gp39; CD154; CD4L; HIGM1; T-BAM; TNFSF5; hCD4L; CD4 ligand; CD4-L; T-cell antigen Gp39; TNF-related activation protein; Tumor necrosis factor ligand superfamily member 5; CD4LG

Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.