ALEXA FLUOR 647 Rabbit anti-Mouse CCR7/CD197 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated [IgG]

EBI1; CCR-7; CD197; Ebi1h; Cdw197; Cmkbr7; CC-CKR-7; C-C chemokine receptor type 7; C-C CKR-7; Epstein-Barr virus-induced G-protein coupled receptor 1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; Ccr7

CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.