Unconjugated Rabbit anti-Human, Mouse, Rat Caveolin-1 Polyclonal Antibody [IgG]

CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; Caveolin-1; CAV1; CAV

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.