Unconjugated Rabbit anti-Human, Mouse, Rat Calreticulin Polyclonal Antibody [IgG]

RO; CRT; SSA; cC1qR; HEL-S-99n; Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 6; ERp6; HACBP; grp6; CALR; CRTC

Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).