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Hana Hodoši (Hrutková)
phone+421 917 709 186 mailhodosi@ibiotech.sk Všechny kontaktyarrow

ALEXA FLUOR 647 Rabbit anti-Human, Mouse, Rat CACNA1S Polyclonal Antibody, ALEXA FLUOR 647 Conjugated [IgG]

Výrobca: Bioss Katalógové č .: bs-9925R-A647 Aplikácie: Imunofluorescencia Reaktivita: Human, Mouse, Rat Pôvod: Rabbit Klonalita: Polyclonal Konjugáty: AlexaFluor647 Laser: 633 nm (červený) Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:

Voltage-dependent L-type calcium channel subunit alpha-1S; Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle; Voltage-gated calcium channel subunit alpha Cav1.1; CACNA1S; CACH1; CACN1; CACNL1A3

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.

100ul
519,20 EUR
s DPH
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