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ALEXA FLUOR 555 Rabbit anti-Human, Mouse, Rat CFLAR Polyclonal Antibody, ALEXA FLUOR 555 Conjugated [IgG]
Výrobca: Bioss Katalógové č .: bs-0119R-A555 Aplikácie: Imunofluorescencia, Prietoková cytometria Reaktivita: Human, Mouse, Rat Pôvod: Rabbit Klonalita: Polyclonal Konjugáty: Alexa Fluor 555 Laser: 550 nm (zeleno-žltý) Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1; CASP8 and FADD-like apoptosis regulator; Caspase homolog; Caspase-eight-related protein; Caspase-like apoptosis regulatory protein; Cellular FLICE-like inhibitory protein; FADD-like antiapoptotic molecule 1; Inhibitor of FLICE; MACH-related inducer of toxicity; Usurpin; CFLAR
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.