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Unconjugated Rabbit anti-Human BMI1 Polyclonal Antibody [IgG]
Výrobca: Bioss Katalógové č .: bs-2999R Aplikácie: Western Blot, Imunofluorescencia, Imunohistochémia, Prietoková cytometria, ELISA, ELISPOT Reaktivita: Human Pôvod: Rabbit Klonalita: Polyclonal Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:PCGF4; RNF51; FLVI2/BMI1; Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; BMI1
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
100ul
415,80 EUR
s DPH