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Biotin Mouse anti-Human, Mouse, Rat HP1 alpha Monoclonal Antibody, Biotin Conjugated [IgG]
Výrobca: Bioss Katalógové č .: bsm-33377M-Biotin Aplikácie: Western Blot Reaktivita: Human, Mouse, Rat Pôvod: Mouse Klonalita: Monoclonal Konjugáty: Biotin/Purifikovaná Laser: Ostatné Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:Antigen p25; HP1-_; CBX5; CBX5_HUMAN; Chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox homolog 5; Chromobox protein homolog 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1 homolog alpha; HP1 alpha; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha.
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.