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FITC Mouse anti-Human, Mouse, Rat Fibronectin (1B9) Monoclonal Antibody , FITC Conjugated [IgG]
Výrobca: Bioss Katalógové č .: bsm-33143M-FITC Aplikácie: Imunofluorescencia Reaktivita: Human, Mouse, Rat Pôvod: Mouse Klonalita: Monoclonal Konjugáty: FITC Laser: 488 nm (modrý) Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:Fibronectin; FN1; Cold-insoluble globulin; CIG
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.