ALEXA FLUOR 750 Rabbit anti-Human, Mouse, Rat C9orf59 Polyclonal Antibody, ALEXA FLUOR 750 Conjugated [IgG]

C9orf59; Chromosome 9 open reading frame 59; Family with sequence similarity 78, member A; FLJ00024; Hypothetical protein LOC286336;FAM78A.

Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The FAM78A gene product has been provisionally designated FAM78A pending further characterization.