Unconjugated Rabbit anti-Human, Mouse, Rat Rad51 (11D1) Monoclonal Antibody [IgG]

DNA repair protein RAD51 homolog 1; RAD51 homolog A; HsRAD51; hRAD51; RAD51; RAD51A; RECA; BRCC5; FANCR; MRMV2; HsT16930.

Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.