Unconjugated Rabbit anti-Human, Mouse, Rat IMPDH2 (2H4) Monoclonal Antibody [IgG]

Inosine-5'-monophosphate dehydrogenase 2; IMPDH-II, IMP dehydrogenase 2; IMPD 2; IMPDH 2; IMPDH2; IMPD2

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.