Unconjugated Rabbit anti-Human, Mouse, Rat HMGB1 (5H4 ) Monoclonal Antibody [IgG]

High mobility group protein B1, High mobility group protein 1, HMG-1

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).