Unconjugated Rabbit anti-Human, Mouse, Rat Elongation factor 1-gamma Monoclonal Antibody [IgG]

2610301D06Rik antibody, AA407312 antibody, eEF 1B gamma antibody, EEF 1G antibody, eEF-1B gamma antibody, EEF1G antibody, EF 1 gamma antibody, EF 1G antibody, EF-1-gamma antibody, EF1 gamma antibody, EF1G antibody, EF1G_HUMAN antibody, Elongation factor 1 gamma antibody, Elongation factor 1-gamma antibody, Eukaryotic translation elongation factor 1 gamma antibody, GIG 35 antibody, GIG35 antibody, MGC103354 antibody, MGC114210 antibody, MGC144723 antibody, MGC144724 antibody, MGC94929 antibody, Pancreatic tumor related protein antibody, PRO1608 antibody, Translation elongation factor eEF 1 gamma chain antibody

EF-1 (elongation factor-1) is a multi-protein complex that is responsible for the delivery of aminoacyl-tRNAs to the ribosome. EF-1 gamma (elongation factor 1-gamma), also known as EEF1G or GIG35, is a 437 amino acid subunit of the EF-1 complex. Expressed in stomach, pancreas, brain, lung, kidney, intestine, liver and spleen, EF-1 gamma contains an N-terminal glutathione transferase domain which is thought to be involved in anchoring the complex to various cellular components. Additionally, EF-1 gamma may play a key role in the assembly of multiprotein complexes containing aminoacyl-tRNA synthetases. Increased expression of EF-1 gamma is associated with pancreatic cancer, suggesting a possible role for EF-1 gamma in the oncogenic transformation process.