Produktová podpora

Hana Hodoši (Hrutková)
phone+421 917 709 186 mailhodosi@ibiotech.sk Všechny kontaktyarrow

Unconjugated Mouse anti- RAB23 Monoclonal Antibody [IgG1]

Výrobca: Bioss Katalógové č .: bsm-51516M Aplikácie: Western Blot, Imunofluorescencia, ELISA, ELISPOT Reaktivita: Ostatné Pôvod: Mouse Klonalita: Monoclonal Podtrieda: IgG1 Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:

DKFZp781H0695; HSPC137; MGC8900; Rab 23; RAB family small GTP binding protein RAB 23; RAB23, member RAS oncogene family; RAB23_HUMAN; Ras related protein Rab 23; Ras-related protein Rab-23.

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

100ul
499,40 EUR
s DPH
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